Integrative analysis of proteomic and MRI data reveals protein associations with brain imaging features in Alzheimer’s disease
This study highlights the critical role of integrating imaging and proteomic data as part of the genotype-to-phenotype roadmap for AD, revealing molecular underpinnings of brain changes and offering a blueprint for the development of targeted therapeutic strategies.
Authors
- Margarita Zachariou (ORCID: https://orcid.org/0000-0001-8950-4077)
- Marios Pantzaris (ORCID: https://orcid.org/0000-0003-2937-384X)
- Anastasia Lambrianides (ORCID: https://orcid.org/0000-0002-9158-7331)
- Sotiroula Afxenti (ORCID: https://orcid.org/0009-0003-5763-6309)
- Eleni M. Loizidou (ORCID: https://orcid.org/0000-0003-2546-5659)
- George M. Spyrou (ORCID: https://orcid.org/0000-0002-2470-3363)
- Marilena M. Bourdakou (ORCID: https://orcid.org/0000-0001-8075-0634)
Institutions
- Cyprus Institute of Neurology and Genetics (CY)
Publication Details
- Journal
- Expert Review of Proteomics
- Published
- 2025-11-07
- DOI
- https://doi.org/10.1080/14789450.2025.2584129
- Citations
- 1
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.16