Biomimetic tri-layered osteochondral scaffold

The tri-layered biomaterial showed good integration with surrounding tissues and new tissue growth promotion after 14 and 30 days post-surgery, with no safety concerns. In light of the development of appropriate postoperative rehabilitation programmes to prevent the risk of early implant failure while avoiding delays and providing a proper recovery path, this study provides support for the new cartilage field trend for this osteochondral scaffold, suggesting the possibility of safely shortening the postoperative rehabilitation phase after surgery.

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Publication Details

Journal
Bone and Joint Research
Published
2025-11-07
DOI
https://doi.org/10.1302/2046-3758.1411.bjr-2024-0426.r2
Primary Topic
Bone Tissue Engineering Materials
Type
article
Field-Weighted Citation Impact
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article

Biomimetic tri-layered osteochondral scaffold

Manuela Salerno, Laura Grillini, Alessandro Di Martino, Giuseppe Filardo et al.
Bone and Joint Research
Bone Tissue Engineering Materials
article

Biomimetic tri-layered osteochondral scaffold

Manuela Salerno, Laura Grillini, Alessandro Di Martino, Giuseppe Filardo, Alessandro Dotti, Elisabetta Galassi, C Luca
article en

Abstract

The tri-layered biomaterial showed good integration with surrounding tissues and new tissue growth promotion after 14 and 30 days post-surgery, with no safety concerns. In light of the development of appropriate postoperative rehabilitation programmes to prevent the risk of early implant failure while avoiding delays and providing a proper recovery path, this study provides support for the new cartilage field trend for this osteochondral scaffold, suggesting the possibility of safely shortening the postoperative rehabilitation phase after surgery.

Bone and Joint ResearchVol. 14(11)
Istituto Ortopedico Rizzoli (IT), Finceramica (Italy) (IT), Università della Svizzera italiana (CH)
Openalex Percentile: Top 68%
Bone Tissue Engineering Materials
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