Health Risk and Toxicological Assessment of Some Heavy Metals in Selected Damaged Bouillon Cubes Consumed in Nigeria A Case Study of Funtua, Katsina State

The safety and suitability of food additives for human consumption are largely dependent on ‎their chemical composition.‎ This study assessed heavy metal contamination in damaged bouillon cubes (Maggi, Knorr, ‎Royco, and Onga) from Funtua LGA using Microwave plasma atomic emission spectrophotometry (MP-AES), and the potential health risks associated with the consumption of these damaged cubes were also evaluated. ‎Concentrations ranged from 2.21–4.24 mg/kg (Cd), 1.01–3.01 mg/kg (Co), 1.01–2.21 mg/kg ‎‎(Ni), 2.21–6.20 mg/kg (Pb), and 0.21–0.56 mg/kg (Zn), with all except Zn exceeding ‎FAO/WHO limits. Estimated daily intakes(EDIs) for Cd, Co, Ni, and Zn were above USEPA tolerable values, while Hazard quotients‎HQs were <1. However, Hazard indices HI exceeded 1 in Maggi and Royco, and Cancer risk (CR) values for all metals ‎were above the USEPA acceptable risk range, indicating possible carcinogenic risk. No ‎significant variation was observed among brands (p > 0.05). These findings suggest potential ‎public health hazards from the consumption of damaged bouillon cubes, warranting stricter ‎regulation and monitoring‎.

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Journal
International Journal of Pharmacology and Toxicology
Published
2025-11-06
DOI
https://doi.org/10.14419/p5rn4366
Primary Topic
Heavy metals in environment
Type
article
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article

Health Risk and Toxicological Assessment of Some Heavy Metals in Selected Damaged Bouillon Cubes Consumed in Nigeria A Case Study of Funtua, Katsina State

Hassan Ismail Musa, Kabir Rawayau Zainab, Aminu Mustapha
International Journal of Pharmacology and Toxicology
Heavy metals in environment
article

Health Risk and Toxicological Assessment of Some Heavy Metals in Selected Damaged Bouillon Cubes Consumed in Nigeria A Case Study of Funtua, Katsina State

Hassan Ismail Musa, Kabir Rawayau Zainab, Aminu Mustapha
article en

Abstract

The safety and suitability of food additives for human consumption are largely dependent on ‎their chemical composition.‎ This study assessed heavy metal contamination in damaged bouillon cubes (Maggi, Knorr, ‎Royco, and Onga) from Funtua LGA using Microwave plasma atomic emission spectrophotometry (MP-AES), and the potential health risks associated with the consumption of these damaged cubes were also evaluated. ‎Concentrations ranged from 2.21–4.24 mg/kg (Cd), 1.01–3.01 mg/kg (Co), 1.01–2.21 mg/kg ‎‎(Ni), 2.21–6.20 mg/kg (Pb), and 0.21–0.56 mg/kg (Zn), with all except Zn exceeding ‎FAO/WHO limits. Estimated daily intakes(EDIs) for Cd, Co, Ni, and Zn were above USEPA tolerable values, while Hazard quotients‎HQs were <1. However, Hazard indices HI exceeded 1 in Maggi and Royco, and Cancer risk (CR) values for all metals ‎were above the USEPA acceptable risk range, indicating possible carcinogenic risk. No ‎significant variation was observed among brands (p > 0.05). These findings suggest potential ‎public health hazards from the consumption of damaged bouillon cubes, warranting stricter ‎regulation and monitoring‎.

International Journal of Pharmacology and ToxicologyVol. 13(2)
State Duma (RU), Kaduna Polytechnic (NG), Bayero University Kano (NG)
Openalex Percentile: Top 74%
Heavy metals in environment
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