Integrative Assessment of TyG Index, FIB-4, and eGFR as Composite Predictors of Metabolic Risk Clusters in Adults
The combined use of TyG, FIB-4, and eGFR provides complementary insight into the metabolic-hepatic-renal continuum. These indices highlight progressive insulin resistance, hepatic stress, and subclinical renal involvement, supporting their utility as accessible tools for early identification of high-risk metabolic phenotypes.
Authors
- Daniela Florina Trifan (ORCID: https://orcid.org/0009-0009-1023-9254)
- Andrada Florina Moldovan (ORCID: https://orcid.org/0000-0002-4435-6848)
- Florica Ramona Dorobanțu (ORCID: https://orcid.org/0000-0001-7036-6030)
- Mihaela Simona Popoviciu (ORCID: https://orcid.org/0000-0003-0006-0102)
- Felicia Manole (ORCID: https://orcid.org/0000-0002-2153-1148)
- Timea Claudia Ghitea (ORCID: https://orcid.org/0000-0001-8981-1958)
- Lavinia Mariș
- Petru Cornel Domocos (ORCID: https://orcid.org/0009-0000-3469-5144)
Institutions
- University of Oradea (RO)
- The Welding Institute (GB)
- Vasile Goldis Western University of Arad (RO)
Publication Details
- Journal
- Metabolites
- Published
- 2025-11-07
- DOI
- https://doi.org/10.3390/metabo15110729
- Citations
- 2
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 2.86