Clinical Utility of Opportunistic Genome-Wide cfDNA Prenatal Screening in Intermediate-Risk Pregnancies
Several confirmed anomalies were clinically significant and would not have been detected through conventional screening. Opportunistic use of expanded NIPT enables the detection of additional clinically relevant abnormalities, potentially improving obstetric management without substantially increasing invasive testing.
Authors
- Mercedes Sobreviela Laserrada
- Mauricio Tajada (ORCID: https://orcid.org/0000-0003-4720-8231)
- Carmen Orellana (ORCID: https://orcid.org/0000-0003-4271-5859)
- José Cervera (ORCID: https://orcid.org/0000-0001-8252-1106)
- Carmen Lahuerta Pueyo
- Laia Pedrola (ORCID: https://orcid.org/0000-0002-3031-6124)
- María Pilar Arruebo (ORCID: https://orcid.org/0000-0002-2114-0577)
- Sebastián Menao (ORCID: https://orcid.org/0000-0002-1817-4549)
- Mónica Rosello (ORCID: https://orcid.org/0000-0001-9234-2953)
- Beatriz Braña Marcos (ORCID: https://orcid.org/0000-0003-4752-7275)
- J. Pascual (ORCID: https://orcid.org/0000-0002-5869-4450)
- Ramiro Quiroga (ORCID: https://orcid.org/0000-0003-4562-3319)
Institutions
- Universidad de Zaragoza (ES)
- Hospital Universitari i Politècnic La Fe (ES)
- Hospital Universitario Miguel Servet (ES)
- Zaragoza Logistics Center (ES)
- Hospital Clínico Universitario Lozano Blesa (ES)
Publication Details
- Journal
- Genes
- Published
- 2025-11-07
- DOI
- https://doi.org/10.3390/genes16111344
- Citations
- 1
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 3.49