Curcumin attenuates liver injury by modulating the AGE–RAGE axis and metabolic homeostasis in high-fat diet/streptozotocin-induced type 2 diabetic mice
CUR protects against diabetic liver injury by inhibiting AGE-RAGE-induced inflammation and metabolic dysregulation. The protective mechanism involves modulation of the AGE-RAGE axis and restoration of metabolic homeostasis.
Authors
- Xiaoyan Bi
- Jun‐Yu Ma (ORCID: https://orcid.org/0000-0002-3339-7863)
- Chunmei Zhang (ORCID: https://orcid.org/0000-0002-2698-3602)
- Xuexun Li (ORCID: https://orcid.org/0000-0002-6554-7010)
- Mengyao Li (ORCID: https://orcid.org/0009-0006-1591-3760)
- Hongsong Li (ORCID: https://orcid.org/0000-0002-5681-3073)
- Yang Jiang (ORCID: https://orcid.org/0000-0001-9066-9418)
- Xin Zhao
- Fuli Ya
- Qin Gao (ORCID: https://orcid.org/0000-0002-5976-8749)
- Benhua Zeng (ORCID: https://orcid.org/0000-0002-8043-3900)
Institutions
- Jining Medical University (CN)
- Dali University (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-11-07
- DOI
- https://doi.org/10.3389/fnut.2025.1710380
- Primary Topic
- Advanced Glycation End Products research
- Type
- article
- Field-Weighted Citation Impact
- 0.00