Chromosome-scale genome assembly and annotation of Saccharina sculpera

Saccharina sculpera is a brown alga (kelp) that is rich in fucoidan (a sulphated heteropolysaccharide) and has shown great potential for medical applications. However, fucoidan accumulation mechanisms in S. sculpera have not yet been elucidated owing to the absence of its genome assembly. In this research, we generated a chromosome-level genome of S. sculpera using Illumina, PacBio HiFi, and high-throughput chromosome conformation capture sequencing technologies. The assembled genome was 726.56 Mb in size, with a contig N50 of 1.08 Mb and scaffold N50 of 19.12 Mb. Approximately 98% of the genomic sequences were ultimately anchored to 34 pseudo-chromosomes. Totally, 25,685 protein-coding genes were identified, of which 86.42% were functionally annotated. Additionally, 438.5 Mb repeat sequences were predicted, which accounted for 60.26% of the assembled genome. The chromosome-level genome of S. sculpera offers an invaluable genetic resource for investigating the molecular mechanism underlying fucoidan accumulation in brown algae.

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Publication Details

Journal
Scientific Data
Published
2025-11-07
DOI
https://doi.org/10.1038/s41597-025-06033-1
Citations
1
Primary Topic
Seaweed-derived Bioactive Compounds
Type
article
Field-Weighted Citation Impact
2.27

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article

Chromosome-scale genome assembly and annotation of Saccharina sculpera

Lihao Guo, Weiwei Wang, Xiaojie Li, Quansheng Zhang et al.
1 citations
Scientific Data
Seaweed-derived Bioactive Compounds
2.27
article

Chromosome-scale genome assembly and annotation of Saccharina sculpera

Lihao Guo, Weiwei Wang, Xiaojie Li, Quansheng Zhang, Mingyu Zhong
article en
1 citations

Abstract

Saccharina sculpera is a brown alga (kelp) that is rich in fucoidan (a sulphated heteropolysaccharide) and has shown great potential for medical applications. However, fucoidan accumulation mechanisms in S. sculpera have not yet been elucidated owing to the absence of its genome assembly. In this research, we generated a chromosome-level genome of S. sculpera using Illumina, PacBio HiFi, and high-throughput chromosome conformation capture sequencing technologies. The assembled genome was 726.56 Mb in size, with a contig N50 of 1.08 Mb and scaffold N50 of 19.12 Mb. Approximately 98% of the genomic sequences were ultimately anchored to 34 pseudo-chromosomes. Totally, 25,685 protein-coding genes were identified, of which 86.42% were functionally annotated. Additionally, 438.5 Mb repeat sequences were predicted, which accounted for 60.26% of the assembled genome. The chromosome-level genome of S. sculpera offers an invaluable genetic resource for investigating the molecular mechanism underlying fucoidan accumulation in brown algae.

Scientific DataVol. 12(1)
Yantai University (CN), Shandong Marine Resource and Environment Research Institute (CN), Luye Pharma (China) (CN), Shandong Institute of Business and Technology (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 9%
Seaweed-derived Bioactive Compounds
2.27
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Chromosome-scale genome assembly and annotation of Saccharina sculpera — Lihao Guo, Weiwei Wang, et al. · Scientific Data (2025) | TGRS Research Map | TGRS