Intravenous magnesium and methocarbamol for acute pain crises in refractory trigeminal neuralgia: A retrospective analysis
A 3-day IV infusion protocol combining magnesium sulfate and methocarbamol, with or without adjunctive ASMs, was associated with rapid, meaningful pain relief in most patients with acute TN pain crises. Larger, prospective studies are warranted to further investigate and confirm the effectiveness of this IV treatment strategy for managing this challenging neurological condition.
Authors
- Harpreet Kaur (ORCID: https://orcid.org/0000-0002-2836-7053)
- Victor Lomachinsky (ORCID: https://orcid.org/0000-0002-2306-6673)
- Payal Soni
- Bradley Ong (ORCID: https://orcid.org/0000-0001-6507-1967)
- R. Yu. Popov (ORCID: https://orcid.org/0000-0001-5716-9593)
- Nymisha Mandava (ORCID: https://orcid.org/0000-0002-8338-8164)
Institutions
- Cleveland Clinic (US)
- The Neurological Institute (US)
Publication Details
- Journal
- Headache The Journal of Head and Face Pain
- Published
- 2025-11-07
- DOI
- https://doi.org/10.1111/head.15097
- Primary Topic
- Trigeminal Neuralgia and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00