Mutational Landscape and Clinical Impact of SPEN Mutations in Patients with Chronic Lymphocytic Leukemia
These data show that <i>SPEN</i> mutations in CLL are associated with adverse prognostic impact and should be included in sequencing assays performed for the prognostic workup of CLL patients.
Authors
- L. Jeffrey Medeiros (ORCID: https://orcid.org/0000-0001-6577-8006)
- C. Cameron Yin (ORCID: https://orcid.org/0000-0001-6630-4128)
- Carlos E. Bueso‐Ramos (ORCID: https://orcid.org/0000-0003-0180-7124)
- Keyur P. Patel (ORCID: https://orcid.org/0000-0001-5081-2427)
- Siba El Hussein (ORCID: https://orcid.org/0000-0002-1338-7107)
- Hong Fang (ORCID: https://orcid.org/0000-0003-1780-5959)
- Roland L. Bassett (ORCID: https://orcid.org/0000-0002-4534-2042)
- Andres Quesada (ORCID: https://orcid.org/0000-0002-5304-7828)
- Nitin B. Jain (ORCID: https://orcid.org/0000-0002-4362-8522)
- Mark J. Routbort (ORCID: https://orcid.org/0000-0003-4860-261X)
- Chi Young Ok (ORCID: https://orcid.org/0000-0002-6822-7880)
- Sanam Loghavi (ORCID: https://orcid.org/0000-0001-8980-3202)
- Sofía Garcés
- Jan A. Burger (ORCID: https://orcid.org/0000-0002-6177-7572)
- Rashmi Kanagal‐Shamanna (ORCID: https://orcid.org/0000-0001-7829-5249)
- Richard K. Yang (ORCID: https://orcid.org/0000-0003-0433-8626)
- Fatima Zahra Jelloul (ORCID: https://orcid.org/0000-0002-3791-3204)
- Sarah Pasyar
- Sa A. Wang (ORCID: https://orcid.org/0000-0001-9385-9911)
- William G. Wierda (ORCID: https://orcid.org/0000-0002-7357-270X)
- Wei Wang (ORCID: https://orcid.org/0000-0001-6821-4556)
- Pei Lin (ORCID: https://orcid.org/0000-0002-9844-945X)
- Anindita Ghosh (ORCID: https://orcid.org/0000-0002-4391-1811)
- Priyatharsini Nirmalanantham
Institutions
- The University of Texas MD Anderson Cancer Center (US)
- University of Vermont Medical Center (US)
Publication Details
- Journal
- Cancers
- Published
- 2025-11-06
- DOI
- https://doi.org/10.3390/cancers17213586
- Primary Topic
- Chronic Lymphocytic Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00