Mutational Landscape and Clinical Impact of SPEN Mutations in Patients with Chronic Lymphocytic Leukemia

These data show that <i>SPEN</i> mutations in CLL are associated with adverse prognostic impact and should be included in sequencing assays performed for the prognostic workup of CLL patients.

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Publication Details

Journal
Cancers
Published
2025-11-06
DOI
https://doi.org/10.3390/cancers17213586
Primary Topic
Chronic Lymphocytic Leukemia Research
Type
article
Field-Weighted Citation Impact
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article

Mutational Landscape and Clinical Impact of SPEN Mutations in Patients with Chronic Lymphocytic Leukemia

L. Jeffrey Medeiros, C. Cameron Yin, Carlos E. Bueso‐Ramos, Keyur P. Patel et al.
Cancers
Chronic Lymphocytic Leukemia Research
article

Mutational Landscape and Clinical Impact of SPEN Mutations in Patients with Chronic Lymphocytic Leukemia

L. Jeffrey Medeiros, C. Cameron Yin, Carlos E. Bueso‐Ramos, Keyur P. Patel, Siba El Hussein, Hong Fang, Roland L. Bassett, Andres Quesada, Nitin B. Jain, Mark J. Routbort, Chi Young Ok, Sanam Loghavi, Sofía Garcés, Jan A. Burger, Rashmi Kanagal‐Shamanna, Richard K. Yang, Fatima Zahra Jelloul, Sarah Pasyar, Sa A. Wang, William G. Wierda, Wei Wang, Pei Lin, Anindita Ghosh, Priyatharsini Nirmalanantham
article en

Abstract

These data show that <i>SPEN</i> mutations in CLL are associated with adverse prognostic impact and should be included in sequencing assays performed for the prognostic workup of CLL patients.

CancersVol. 17(21)
The University of Texas MD Anderson Cancer Center (US), University of Vermont Medical Center (US)
Openalex Percentile: Top 54%
Chronic Lymphocytic Leukemia Research
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Mutational Landscape and Clinical Impact of SPEN Mutations in Patients with Chronic Lymphocytic Leukemia — L. Jeffrey Medeiros, C. Cameron Yin, et al. · Cancers (2025) | TGRS Research Map | TGRS