A Large Room for Improvement Concerning the Management of Relapsed Refractory Large B-cell Lymphoma in Türkiye: Real-World Outcomes in the Setting Without Access to T-Cell Redirecting Therapies
The current therapeutic strategy of intensive chemoimmunotherapy followed by autologous transplantation yields a reasonable chance of survival for only one-fifth of patients. The findings of this study emphasize the urgent need for expanding access to T-cell redirecting approaches in R/R LBCL for early progressors, transplant-ineligible cases, and patients who fail intensive second-line regimens.
Authors
- Fevzi Altuntaş
- Turgay Ulaş (ORCID: https://orcid.org/0000-0001-9332-663X)
- Fatma Keklik Karadağ (ORCID: https://orcid.org/0000-0001-6078-5944)
- Işık Atagündüz (ORCID: https://orcid.org/0000-0002-7876-6896)
- Eda Nuhoğlu Kantarcı (ORCID: https://orcid.org/0000-0001-6346-349X)
- Tuğrul Elverdi (ORCID: https://orcid.org/0000-0001-9496-5353)
- Meral Uluköylü Mengüç (ORCID: https://orcid.org/0000-0002-4303-9488)
- Deniz Gören
- Olga Meltem Akay (ORCID: https://orcid.org/0000-0002-6759-1939)
- Elif Birtaş Ateşoğlu (ORCID: https://orcid.org/0000-0002-2596-4493)
- Burhan Ferhanoğlu (ORCID: https://orcid.org/0000-0002-4257-549X)
- Sinem Civriz Bozdağ (ORCID: https://orcid.org/0000-0001-8359-7794)
- Ebru Pekgüç (ORCID: https://orcid.org/0009-0005-7628-1712)
- Öner Doğan
- Umur Hatipoğlu (ORCID: https://orcid.org/0000-0002-0863-6471)
- Simge Erdem (ORCID: https://orcid.org/0000-0001-8095-5445)
- Abdülkadir Şahin (ORCID: https://orcid.org/0000-0002-8426-792X)
- Emre Osmanbaşoğlu
- Derya Demir (ORCID: https://orcid.org/0000-0002-6333-8856)
- Asu Fergün Yılmaz (ORCID: https://orcid.org/0000-0001-5118-6894)
- Serdar Örnek
- Nurullah Okumuş (ORCID: https://orcid.org/0000-0001-6082-0818)
- Mustafa Nuri Yenerel (ORCID: https://orcid.org/0000-0002-6473-1342)
- Mustafa Murat Özbalak
- Özgür Mehtap (ORCID: https://orcid.org/0000-0002-5603-1178)
- Muhlis Cem Ar (ORCID: https://orcid.org/0000-0002-0332-9253)
- Güray Saydam (ORCID: https://orcid.org/0000-0001-8646-1673)
- Taner Tan
- Mert Seyhan
- Umut Yılmaz (ORCID: https://orcid.org/0000-0002-8672-0679)
- Tayfur Toptaş
- Mehmet Sinan Dal
- Tuğba Zorlu (ORCID: https://orcid.org/0000-0001-5108-381X)
- Esra Terzi Demirsoy
- Ali Durdu
- Merve Apaydın Kayer
- Ahmet Bahadır Ak
Institutions
- Yeditepe University (TR)
- Koç University (TR)
- Ankara University (TR)
- University of Health Science (KH)
- Ege University (TR)
- Ankara Onkoloji Eğitim ve Araştırma Hastanesi (TR)
- Memorial Sisli Hospital (TR)
- Istanbul University-Cerrahpaşa (TR)
- Sağlık Bilimleri Üniversitesi (TR)
- Ankara Yıldırım Beyazıt University (TR)
- Amerikan Hastanesi (TR)
- Kocaeli Üniversitesi (TR)
- Istanbul University (TR)
- Marmara University (TR)
Publication Details
- Journal
- Turkish Journal of Hematology
- Published
- 2025-11-07
- DOI
- https://doi.org/10.4274/tjh.galenos.2025.2025.0352
- Citations
- 1
- Primary Topic
- Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.47