Mitochondrial Function Is Required to Preserve Viability of Stem Cells From the Apical Papilla Following <i>Porphyromonas endodontalis</i> Infection
SCAP could maintain cell viability after short-term P. endodontalis infection. The underlying mechanism may involve mitochondrial fission and mitophagy, which appear to function as key protective processes enabling SCAP to counteract infection-induced cellular damage. This study helps elucidate the molecular basis of SCAP survival under bacterial infection.
Authors
- Xincheng Wang (ORCID: https://orcid.org/0000-0002-7402-2136)
- Ning Yang (ORCID: https://orcid.org/0000-0001-5121-7208)
- Junpeng Li (ORCID: https://orcid.org/0000-0002-2170-8230)
- AN-CONG WANG
- Xiaodan Chen (ORCID: https://orcid.org/0000-0003-1772-1958)
- L. Shang (ORCID: https://orcid.org/0000-0002-9218-2408)
- Mengchun Gao (ORCID: https://orcid.org/0000-0002-9690-2636)
- Si Yu (ORCID: https://orcid.org/0000-0002-9326-9898)
Institutions
- Shenyang Center for Disease Control and Prevention (CN)
- China Medical University (CN)
Publication Details
- Journal
- International Endodontic Journal
- Published
- 2025-11-07
- DOI
- https://doi.org/10.1111/iej.70058
- Primary Topic
- Endodontics and Root Canal Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00