Subclinical Tuberculosis Diagnosis in Lusaka, Zambia: A Case Report

Identifying subclinical tuberculosis (TB) remains a significant challenge due to the absence of typical symptoms, the lack of diagnostic tests to distinguish disease states along the TB clinical spectrum, and the inability of plain radiography to pick up subtle changes associated with it. In this paper, we present two instances of subclinical TB identified in a high TB burden setting, highlighting the difficulties in diagnosis, challenges in treatment adherence and completion, and the risk of transmission.

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Publication Details

Journal
Cureus
Published
2025-11-06
DOI
https://doi.org/10.7759/cureus.96269
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Subclinical Tuberculosis Diagnosis in Lusaka, Zambia: A Case Report

Monde Muyoyeta, Kondwelani Mateyo, Nsala Sanjase, Seke Muzazu et al.
Cureus
Tuberculosis Research and Epidemiology
article

Subclinical Tuberculosis Diagnosis in Lusaka, Zambia: A Case Report

Monde Muyoyeta, Kondwelani Mateyo, Nsala Sanjase, Seke Muzazu, Brian Shuma, Evelyn K Ngandu
article en

Abstract

Identifying subclinical tuberculosis (TB) remains a significant challenge due to the absence of typical symptoms, the lack of diagnostic tests to distinguish disease states along the TB clinical spectrum, and the inability of plain radiography to pick up subtle changes associated with it. In this paper, we present two instances of subclinical TB identified in a high TB burden setting, highlighting the difficulties in diagnosis, challenges in treatment adherence and completion, and the risk of transmission.

CureusVol. 17(11)
Centre for Infectious Disease Research in Zambia (ZM), University Teaching Hospital (ZM), University of Zambia (ZM)
Openalex Percentile: Top 61%
Tuberculosis Research and Epidemiology
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