Development and validation of a predictive nomogram for severe adverse drug reactions: a dual-center pharmacovigilance study
This study established a predictive nomogram for SADRs based on LR through comparative analysis of three ML approaches. The developed nomogram enables clinically meaningful risk stratification for SADRs, facilitating prophylactic surveillance of high-risk populations.
Authors
- Xinjing Wu
- Yan Cai (ORCID: https://orcid.org/0009-0000-2751-0455)
- Wei Bu (ORCID: https://orcid.org/0000-0002-1747-4945)
- Chengyu Wang
Institutions
- Yuncheng University (CN)
- Zunyi Medical University (CN)
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-11-07
- DOI
- https://doi.org/10.3389/fphar.2025.1669995
- Primary Topic
- Pharmacovigilance and Adverse Drug Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00