Therapeutic potential of citral on lipopolysaccharide‐induced oxidative organopathy in rat
Citral gives strong protection against LPS-induced hepatorenal injuries, likely mediated through its antioxidant, lipid regulatory and anti-inflammatory actions. These results highlight citral's translational potential as a natural therapeutic agent for preventing or treating endotoxin-mediated organ damage, suggesting promise for future clinical applications in sepsis or systemic inflammatory disorders. © 2025 Society of Chemical Industry.
Authors
- Amani Omrani (ORCID: https://orcid.org/0009-0001-6213-4835)
- Fatma Arrari
- Hichem Sebaï (ORCID: https://orcid.org/0000-0003-0131-1401)
- Mohamed‐Amine Jabri (ORCID: https://orcid.org/0000-0003-2668-7245)
- Jacob Lorenzo‐Morales (ORCID: https://orcid.org/0000-0002-7683-2888)
- Soumaya Hajaji (ORCID: https://orcid.org/0009-0001-5283-917X)
- Meriam Ben Youssef (ORCID: https://orcid.org/0009-0008-8311-9133)
Institutions
- Universidad de La Laguna (ES)
- Hospital Universitario de Canarias (ES)
- Instituto de Salud Carlos III (ES)
- Centro de Investigación Biomédica en Red (ES)
- University of Jendouba (TN)
Publication Details
- Journal
- Journal of the Science of Food and Agriculture
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1002/jsfa.70298
- Primary Topic
- Drug-Induced Hepatotoxicity and Protection
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Instituto de Salud Carlos III