Palladium-Catalyzed Oxidative Heck-Type Reaction of Allylic Acetates with Arylhydrazines as Arylation Reagents via β-OAc Elimination
A palladium-catalyzed oxidative Heck-type arylation of allylic acetates via a β-OAc elimination process was developed under base- and acid-free conditions. In this reaction, arylhydrazines were utilized as "green" arylation reagents, producing nitrogen gas (N<sub>2</sub>) and water (H<sub>2</sub>O) as byproducts and yielding a series of allyl arenes in moderate to good yields. Furthermore, this reaction is characterized by its simplicity, mild conditions, broad substrate scope, and good functional group tolerance.
Authors
- Guiqin Chen (ORCID: https://orcid.org/0000-0002-2820-1344)
- Zhenming Zhang (ORCID: https://orcid.org/0000-0001-8550-5398)
- Shubing Shu
- Xue Yao (ORCID: https://orcid.org/0000-0001-7360-2561)
- Zheqing Huang (ORCID: https://orcid.org/0000-0002-4916-1492)
- Tao Wang (ORCID: https://orcid.org/0000-0002-4971-2020)
- Meng Yu (ORCID: https://orcid.org/0009-0000-4988-8571)
- Yongli Zhao (ORCID: https://orcid.org/0000-0002-9543-1019)
- Jian Peng (ORCID: https://orcid.org/0000-0002-7948-2609)
Institutions
- Korea Testing Certification (KR)
- BioMimetic Systems (United States) (US)
- Jiangxi Normal University (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-11-07
- DOI
- https://doi.org/10.1021/acs.joc.5c02034
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00