Implementation of a diagnostic stewardship initiative for healthcare facility-onset <i>Clostridioides difficile</i> infection

We aimed to improve diagnostic accuracy for healthcare facility-onset <i>Clostridioides difficile</i> (HO-CDI) infection by removing the result for <i>C. difficile</i> from the multiplex gastrointestinal polymerase chain reaction (PCR). The intervention resulted in an increase in positive PCR tests meeting testing criteria and decrease in median number of HO-CDI per month.

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Publication Details

Journal
Infection Control and Hospital Epidemiology
Published
2025-11-07
DOI
https://doi.org/10.1017/ice.2025.10343
Primary Topic
Clostridium difficile and Clostridium perfringens research
Type
article
Field-Weighted Citation Impact
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article

Implementation of a diagnostic stewardship initiative for healthcare facility-onset Clostridioides difficile infection

Lisa Townsend, Bernadette Thompson, Caitlin Bettger, John L Kiley
Infection Control and Hospital Epidemiology
Clostridium difficile and Clostridium perfringens research
article

Implementation of a diagnostic stewardship initiative for healthcare facility-onset Clostridioides difficile infection

Lisa Townsend, Bernadette Thompson, Caitlin Bettger, John L Kiley
article en

Abstract

We aimed to improve diagnostic accuracy for healthcare facility-onset <i>Clostridioides difficile</i> (HO-CDI) infection by removing the result for <i>C. difficile</i> from the multiplex gastrointestinal polymerase chain reaction (PCR). The intervention resulted in an increase in positive PCR tests meeting testing criteria and decrease in median number of HO-CDI per month.

Infection Control and Hospital EpidemiologyVol. 47(1)
United States Army Medical Command (US), Brooke Army Medical Center (US), Wilford Hall Ambulatory Surgical Center (US), Tripler Army Medical Center (US), Joint Base San Antonio (US)
Openalex Percentile: Top 61%
Clostridium difficile and Clostridium perfringens research
DOISourceOpenAlex
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Implementation of a diagnostic stewardship initiative for healthcare facility-onset <i>Clostridioides difficile</i> infection — Lisa Townsend, Bernadette Thompson, et al. · Infection Control and Hospital Epidemiology (2025) | TGRS Research Map | TGRS