A Rare Case of <i>t</i> (1; 19) Translocation in Acute Myeloid Leukemia: Evaluation of a High‐Risk Patients
Acute Myeloid Leukemia (AML) is a heterogeneous malignancy arising from the malignant transformation of hematopoietic stem cells, characterized by the accumulation of blasts in the myeloid lineage. While common cytogenetic alterations in AML play a critical role in prognostic classification, rare chromosomal translocations may have distinct impacts on disease biology and treatment response. In this report, we present a high-risk AML case harboring the <i>t</i>(1; 19) translocation. By highlighting the diagnostic and therapeutic challenges posed by this uncommon genetic aberration, this case aims to contribute to clinical practice in the field of hematology.
Authors
- Abdullah Karakuş (ORCID: https://orcid.org/0000-0003-2090-4392)
- Orhan Ayyıldız (ORCID: https://orcid.org/0000-0001-5673-8408)
- Songül Beskisiz (ORCID: https://orcid.org/0000-0001-9893-3586)
Institutions
- Dicle University (TR)
Publication Details
- Journal
- Case Reports in Hematology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1155/crh/4655315
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00