Legionella-induced suppurative cervical lymphadenitis in a child diagnosed by metagenomic next-generation sequencing: a case report

<i>Legionella pneumophila</i>, primarily associated with respiratory infections, rarely causes extrapulmonary disease. Conventional diagnostic methods for <i>Legionella</i> are often limited. Here we report a case of suppurative cervical lymphadenitis caused by <i>L. pneumophila</i>. And we highlight the critical role of mNGS in enabling rapid and accurate pathogen identification, guiding effective targeted therapy for rare and challenging infections.

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Publication Details

Journal
Frontiers in Pediatrics
Published
2025-11-07
DOI
https://doi.org/10.3389/fped.2025.1655298
Primary Topic
Legionella and Acanthamoeba research
Type
article
Field-Weighted Citation Impact
0.00
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article

Legionella-induced suppurative cervical lymphadenitis in a child diagnosed by metagenomic next-generation sequencing: a case report

Jiandong Li, Bowen Li, Yaru Liao
Frontiers in Pediatrics
Legionella and Acanthamoeba research
article

Legionella-induced suppurative cervical lymphadenitis in a child diagnosed by metagenomic next-generation sequencing: a case report

Jiandong Li, Bowen Li, Yaru Liao
article en

Abstract

<i>Legionella pneumophila</i>, primarily associated with respiratory infections, rarely causes extrapulmonary disease. Conventional diagnostic methods for <i>Legionella</i> are often limited. Here we report a case of suppurative cervical lymphadenitis caused by <i>L. pneumophila</i>. And we highlight the critical role of mNGS in enabling rapid and accurate pathogen identification, guiding effective targeted therapy for rare and challenging infections.

Frontiers in PediatricsVol. 13
Jinan Infectious Disease Hospital (CN), Qilu Hospital of Shandong University (CN)
Openalex Percentile: Top 71%
Legionella and Acanthamoeba research
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