Prognostic value of the MDACC–NLR score in extensive-stage small-cell lung cancer treated with first-line chemoimmunotherapy
ECOG ≥1, lung metastasis, and liver metastasis are adverse prognostic factors for ES-SCLC patients receiving first-line chemo-immunotherapy. The MDACC+NLR scoring system provides superior predictive value for treatment outcomes and survival, supporting its potential utility for clinical risk stratification.
Authors
- Jingpeng Liu (ORCID: https://orcid.org/0000-0002-5452-9052)
- Yan Liu (ORCID: https://orcid.org/0000-0001-8998-2482)
- Yudong Wang (ORCID: https://orcid.org/0000-0001-8302-5518)
- Bo Wang (ORCID: https://orcid.org/0000-0003-4172-9271)
- Xue Zhang (ORCID: https://orcid.org/0009-0004-0249-0581)
- Long Wang
- Feng Li (ORCID: https://orcid.org/0000-0002-7961-3728)
- Jing Zuo (ORCID: https://orcid.org/0000-0002-2318-5349)
- Dan Li (ORCID: https://orcid.org/0000-0002-8113-6510)
- Zhisong Fan
- Ning Liu (ORCID: https://orcid.org/0009-0008-5231-1835)
- Hui Jin (ORCID: https://orcid.org/0000-0003-0297-3052)
- Jing Han (ORCID: https://orcid.org/0009-0000-5815-334X)
- Xiaolin Li (ORCID: https://orcid.org/0000-0001-8418-6233)
Institutions
- Hebei Medical University (CN)
- Fourth Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-07
- DOI
- https://doi.org/10.3389/fimmu.2025.1681658
- Citations
- 1
- Primary Topic
- Lung Cancer Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- Natural Science Foundation of Hebei Province
- Wu Jieping Medical Foundation