Bioassay-guided isolation of sesamin and fargesin from the hydroalcoholic stem extract of Zanthoxylum armatum DC. inhibited inflammation in CpG-stimulated conventional type 1 dendritic cells
The results identified bioactive compounds with potential against the pro-inflammatory dendritic cells for the first time. The findings justified the traditional use of <i>Z. armatum</i> DC. as an anti-inflammatory agent.
Authors
- Ningthoujam Indrajit Singh (ORCID: https://orcid.org/0000-0001-8860-325X)
- Naresh C. Bal (ORCID: https://orcid.org/0000-0002-2859-6315)
- C. K. Mukherjee
- Chingakham Brajakishor Singh (ORCID: https://orcid.org/0000-0002-8192-7777)
- Sunil K. Raghav (ORCID: https://orcid.org/0000-0001-9913-4241)
- Wangkheimayum Marjit Singh
- Jerina Soibam
Institutions
- Manipur University (IN)
- Institute of Life Sciences (IN)
- Institute of Bio-Resources and Sustainable Development (IN)
- KIIT University (IN)
- Indian Institute of Technology Bhubaneswar (IN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-11-07
- DOI
- https://doi.org/10.3389/fphar.2025.1687789
- Primary Topic
- Sesame and Sesamin Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Jawaharlal Nehru University