Pulsed electromagnetic field prevents lumbar bone loss in orchiectomy mice without altering systemic iron metabolism
PEMF therapy exerts site-specific protective effects against ORX-induced osteoporosis in the lumbar spine of male mice to partially restore bone formation and reduce resorption. This therapeutic efficacy is independent of any alterations in the systemic iron metabolism. The findings of this study support PEMF application as a potential physical therapy for male osteoporosis while highlighting the need for site-optimized strategies.
Authors
- Mingming Pan
- Jiancheng Yang (ORCID: https://orcid.org/0000-0003-0008-9036)
- Yuhong Zeng (ORCID: https://orcid.org/0000-0002-8805-0066)
- Yan Feng (ORCID: https://orcid.org/0000-0002-2522-2115)
Institutions
- Xi'an Honghui Hospital (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2025-11-07
- DOI
- https://doi.org/10.3389/fbioe.2025.1684162
- Citations
- 1
- Primary Topic
- Electromagnetic Fields and Biological Effects
- Type
- article
- Field-Weighted Citation Impact
- 1.63
Funders
- Bethune Charitable Foundation
- Fundamental Research Funds for the Central Universities