Identification and diagnostic significance of MPO, PRTN3, and CTNND1 as biomarkers in acute hematogenous osteomyelitis in children: a comprehensive analysis using machine learning algorithms
MPO, PRTN3, and CTNND1 are promising biomarkers for the diagnosis and monitoring of AHO in children. Their expression levels correlate with disease severity, making them valuable tools for assessing the progression and treatment efficacy in pediatric AHO. Further research is warranted to explore their potential in clinical applications.
Authors
- Xin Lv
- Jiafei Yang (ORCID: https://orcid.org/0000-0001-7089-1978)
- Kezhi Chen (ORCID: https://orcid.org/0000-0003-0974-1764)
- Jihang Luo (ORCID: https://orcid.org/0000-0001-5351-2622)
- Tianjiu Zhang
- Yu Song (ORCID: https://orcid.org/0000-0002-9092-8958)
Institutions
- Guiyang Medical University (CN)
- Zunyi Medical University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
- First People’s Hospital of Zunyi (CN)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2025-11-07
- DOI
- https://doi.org/10.3389/fped.2025.1565619
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00