Non-invasive imaging biomarkers of cellular injury and proliferation in nasopharyngeal carcinoma: insights from multiparametric MRI
Multiparametric MRI can noninvasively predict short-term response and reflect proliferative status in NPC. Integrating IVIM-derived D with DCE-derived K<sup>trans</sup> and K<sub>ep</sub> improves early prediction of treatment efficacy; V<sub>p</sub> may serve as an imaging surrogate for proliferation.
Authors
- Yang Liu (ORCID: https://orcid.org/0000-0002-2826-7407)
- Mengxi He
- Changjiang Zhao
- Xiong Xiong
- Chengxin Yu (ORCID: https://orcid.org/0000-0002-0319-8839)
- Lisi Xie
Institutions
- China Three Gorges University (CN)
- Wuhan Children's Hospital (CN)
- Yichang Central People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-11-07
- DOI
- https://doi.org/10.3389/fcell.2025.1684620
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00