Direct Immunofluorescence in Immunobullous Disorders of Skin With Histopathological Correlation Among Patients Attending a Tertiary Care Center

DIF is an invaluable diagnostic tool that complements histopathology, enabling accurate differentiation of AIBDs based on antibody type and distribution pattern. Other blistering conditions, including subcorneal pustules and acute inflammatory lesions, showed no or minimal immunoglobulin deposition. These findings highlight the diagnostic utility of DIF in differentiating AIBDs based on the type and intensity of antibody deposition.

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Publication Details

Journal
Cureus
Published
2025-11-06
DOI
https://doi.org/10.7759/cureus.96265
Primary Topic
Autoimmune Bullous Skin Diseases
Type
article
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article

Direct Immunofluorescence in Immunobullous Disorders of Skin With Histopathological Correlation Among Patients Attending a Tertiary Care Center

M Preethi, P Meilung Phom, Anbumozhi Mk
Cureus
Autoimmune Bullous Skin Diseases
article

Direct Immunofluorescence in Immunobullous Disorders of Skin With Histopathological Correlation Among Patients Attending a Tertiary Care Center

M Preethi, P Meilung Phom, Anbumozhi Mk
article en

Abstract

DIF is an invaluable diagnostic tool that complements histopathology, enabling accurate differentiation of AIBDs based on antibody type and distribution pattern. Other blistering conditions, including subcorneal pustules and acute inflammatory lesions, showed no or minimal immunoglobulin deposition. These findings highlight the diagnostic utility of DIF in differentiating AIBDs based on the type and intensity of antibody deposition.

CureusVol. 17(11)
Sree Balaji Dental College and Hospital (IN)
Openalex Percentile: Top 54%
Autoimmune Bullous Skin Diseases
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