Study of Interferon‐Induced Transmembrane Protein 3 Gene Polymorphism and Serum Interferon‐λ3 Level in COVID‐19

We found that the AG genotype and G allele of IFITM3 rs12252 are associated with COVID-19 infection in the Egyptian population but not with severity or outcome. Additionally, serum IFNL3 level is significantly associated with COVID-19 susceptibility but not with severity. It is associated with tachypnea and end-organ failure in severe cases. So, they are independent predictors only for developing COVID-19 infection, but not for developing severe infection.