Association of co-occurrence of gastrointestinal, sleep, and affective symptoms with Helicobacter pylori infection: a monocentric cross-sectional study in China
<i>H. pylori</i> infection was associated with concurrent gastrointestinal discomfort, sleep disturbance, and affective disorders. These findings suggest a unified symptom cluster attributable to <i>H. pylori</i> infection, extending its clinical impact beyond the gastric tract. Recognizing this multidimensional presentation could inform more comprehensive diagnostic and therapeutic strategies for affected patients.
Authors
- Xun Shangguan (ORCID: https://orcid.org/0000-0002-6193-0805)
- J. Liu (ORCID: https://orcid.org/0000-0002-5653-6977)
- Shuyu Yang (ORCID: https://orcid.org/0000-0003-2950-0861)
- Hongfei Ke
- Jielong Wu (ORCID: https://orcid.org/0000-0001-9142-2871)
- Nengjiang Zhao
- Bo Li (ORCID: https://orcid.org/0000-0002-2820-9098)
- Min Chen (ORCID: https://orcid.org/0000-0003-0419-743X)
- Zhihai Zhang (ORCID: https://orcid.org/0000-0003-3686-5789)
- Xin‐Hua Hu (ORCID: https://orcid.org/0000-0001-5038-7651)
- MiaoNa Cai
Institutions
- Guangdong Pharmaceutical University (CN)
- First Affiliated Hospital of Xiamen University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-11-07
- DOI
- https://doi.org/10.3389/fendo.2025.1675866
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Xiamen Municipal Bureau of Science and Technology