MicroRNAs modulated by DPP-4 inhibitor and bedtime NPH insulin therapy in individuals with type 2 diabetes
The upregulated miRNAs are involved in pathways related to insulin signaling, inflammation, and cellular homeostasis and support the hypothesis that sitagliptin exerts pleiotropic effects beyond glycemic control.
Authors
- Aritânia Sousa Santos (ORCID: https://orcid.org/0000-0003-4091-5777)
- Maria Lúcia Corrêa‐Giannella (ORCID: https://orcid.org/0000-0003-3655-4446)
- Sílvia Yumi Bando (ORCID: https://orcid.org/0000-0003-3794-2440)
- Maria Elizabeth Rossi da Silva
Institutions
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-11-07
- DOI
- https://doi.org/10.3389/fendo.2025.1706951
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Universidade de São Paulo
- Faculdade de Medicina da Universidade de São Paulo