Assessment of the risk of discontinuation of tenofovir disoproxil fumarate after delivery and the benefit of continued treatment in patients with immune tolerance

Postpartum discontinuation of TDF poses significant risks for immunotolerant pregnant women, whereas continuing TDF treatment for 144 weeks postpartum demonstrates favorable antiviral efficacy, bone and renal safety profiles.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-11-07
DOI
https://doi.org/10.3389/fmed.2025.1597664
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
0.00

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article

Assessment of the risk of discontinuation of tenofovir disoproxil fumarate after delivery and the benefit of continued treatment in patients with immune tolerance

Minghua Su, Haiping Liang, Jianning Jiang, Hengkai Liang et al.
Frontiers in Medicine
Cytomegalovirus and herpesvirus research
article

Assessment of the risk of discontinuation of tenofovir disoproxil fumarate after delivery and the benefit of continued treatment in patients with immune tolerance

Minghua Su, Haiping Liang, Jianning Jiang, Hengkai Liang, Rongming Wang, Bobin Hu, Yanfei Feng, Huan Liang, Tumei Su, Qingmei Li, Linxian Huang
article en

Abstract

Postpartum discontinuation of TDF poses significant risks for immunotolerant pregnant women, whereas continuing TDF treatment for 144 weeks postpartum demonstrates favorable antiviral efficacy, bone and renal safety profiles.

Frontiers in MedicineVol. 12
Guangxi Medical University (CN), First Affiliated Hospital of GuangXi Medical University (CN), Guangxi Center for Disease Prevention and Control (CN), Tumor Hospital of Guangxi Medical University (CN)
National Natural Science Foundation of China, Guangxi Medical University
Openalex Percentile: Top 56%
Cytomegalovirus and herpesvirus research
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