A Comparative Study of the Effects of Nine CXCR3 Antagonists on Macrophage Function and the Treatment of Acute Lung Injury
All nine CXCR3 antagonists were shown to influence macrophage function to varying degrees and confer protective effects against ALI. These finding suggest that comparative evaluation of CXCR3 antagonists and the discovery of novel compounds may provide new therapeutic targets for the treatment of inflammatory diseases.
Authors
- Wei Gu (ORCID: https://orcid.org/0000-0002-4421-2326)
- Ziyu Wan (ORCID: https://orcid.org/0009-0007-6269-1328)
- Pengbin Wang (ORCID: https://orcid.org/0009-0002-9038-4046)
- Feng Qian (ORCID: https://orcid.org/0000-0002-1949-9193)
- Lexing Li (ORCID: https://orcid.org/0000-0001-7939-7407)
- Zefeng Zhu (ORCID: https://orcid.org/0009-0003-5069-0097)
- Xuan Xu (ORCID: https://orcid.org/0009-0002-8932-621X)
- Guoquan Liu (ORCID: https://orcid.org/0000-0003-3838-0590)
- Tan-Tu Ma (ORCID: https://orcid.org/0009-0007-4169-6218)
- Mengjie Zhang (ORCID: https://orcid.org/0009-0009-1501-1742)
Institutions
- Bengbu Medical College (CN)
- Wuhan Institute of Bioengineering (CN)
- Ministry of Education (KR)
- Wuhan University of Science and Technology (CN)
- Hubei University of Technology (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-10-31
- DOI
- https://doi.org/10.31083/fbl45931
- Primary Topic
- Chemokine receptors and signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00