Quantitative Analysis of Retrograde Trans-Synaptic Retinal Degeneration Based on Lesion Topography

RTSD progression was pronounced in both the pRNFL and mGCIPL during the first 4 years, with greater severity observed in areas topographically linked to the brain lesion. Although RTSD developed regardless of lesion etiology, older age, male gender, severe VFD, intracerebral hemorrhage, and malignant tumors were associated with significantly faster progression.

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Publication Details

Journal
Journal of Neuro-Ophthalmology
Published
2025-10-23
DOI
https://doi.org/10.1097/wno.0000000000002414
Citations
1
Primary Topic
Retinal Development and Disorders
Type
article
Field-Weighted Citation Impact
0.81
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article

Quantitative Analysis of Retrograde Trans-Synaptic Retinal Degeneration Based on Lesion Topography

Byung Ju Lee, Yeji Moon, Young‐Min Lim, Eun‐Jae Lee et al.
1 citations
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Retinal Development and Disorders
0.81
article

Quantitative Analysis of Retrograde Trans-Synaptic Retinal Degeneration Based on Lesion Topography

Byung Ju Lee, Yeji Moon, Young‐Min Lim, Eun‐Jae Lee, Hyunjin Kim
article en
1 citations

Abstract

RTSD progression was pronounced in both the pRNFL and mGCIPL during the first 4 years, with greater severity observed in areas topographically linked to the brain lesion. Although RTSD developed regardless of lesion etiology, older age, male gender, severe VFD, intracerebral hemorrhage, and malignant tumors were associated with significantly faster progression.

Journal of Neuro-Ophthalmology
University of Ulsan (KR)
Openalex Percentile: Top 22%
Retinal Development and Disorders
0.81
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