Dissecting Heterogeneity Reveals Functional Subpopulation of Stem Cells From Human Exfoliated Deciduous Teeth

This study offers a theoretical basis for optimizing SHED-based cell therapeutic strategies. BAMBI⁺ SHEDs, excelling in angiogenesis/chondrogenesis, may be used for tissue-engineered therapies of the clinical disorders such as temporomandibular joint disc regeneration via "vascularize-then-cartilage" strategy.

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Publication Details

Journal
International Dental Journal
Published
2025-11-07
DOI
https://doi.org/10.1016/j.identj.2025.104014
Primary Topic
Osteoarthritis Treatment and Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Dissecting Heterogeneity Reveals Functional Subpopulation of Stem Cells From Human Exfoliated Deciduous Teeth

Yijia Qiu, Yuanyuan Wang, Yuqing Peng, Dan Wang et al.
International Dental Journal
Osteoarthritis Treatment and Mechanisms
article

Dissecting Heterogeneity Reveals Functional Subpopulation of Stem Cells From Human Exfoliated Deciduous Teeth

Yijia Qiu, Yuanyuan Wang, Yuqing Peng, Dan Wang, Man Qin, Yanqiang Zhao, Jingyi Cui
article en

Abstract

This study offers a theoretical basis for optimizing SHED-based cell therapeutic strategies. BAMBI⁺ SHEDs, excelling in angiogenesis/chondrogenesis, may be used for tissue-engineered therapies of the clinical disorders such as temporomandibular joint disc regeneration via "vascularize-then-cartilage" strategy.

International Dental JournalVol. 76(1)
King University (US), Peking University (CN), Peking University School and Hospital of Stomatology (CN)
Openalex Percentile: Top 53%
Osteoarthritis Treatment and Mechanisms
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