Use of bevacizumab for patients with International Federation of Gynecology and Obstetrics stage IIIB to IV epithelial ovarian cancer undergoing primary debulking surgery and its association with oncologic outcomes: a Cancer Registry study

Bevacizumab is frequently used in primary debulking surgery for advanced ovarian cancer. Survival benefits are mainly observed in patients with residual disease, while PARP inhibitor therapy may influence these effects. Real-world evidence complements clinical trials and informs treatment decisions.

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Publication Details

Journal
International Journal of Gynecological Cancer
Published
2025-11-06
DOI
https://doi.org/10.1016/j.ijgc.2025.102770
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Use of bevacizumab for patients with International Federation of Gynecology and Obstetrics stage IIIB to IV epithelial ovarian cancer undergoing primary debulking surgery and its association with oncologic outcomes: a Cancer Registry study

Philipp Morakis, Daria B. Kokh, Irina Surovtsova, Katharina Smetanay et al.
International Journal of Gynecological Cancer
Ovarian cancer diagnosis and treatment
article

Use of bevacizumab for patients with International Federation of Gynecology and Obstetrics stage IIIB to IV epithelial ovarian cancer undergoing primary debulking surgery and its association with oncologic outcomes: a Cancer Registry study

Philipp Morakis, Daria B. Kokh, Irina Surovtsova, Katharina Smetanay, Oliver Zivanovic, Georg Sauer, André Pfob, Andreas Schneeweiß
article en

Abstract

Bevacizumab is frequently used in primary debulking surgery for advanced ovarian cancer. Survival benefits are mainly observed in patients with residual disease, while PARP inhibitor therapy may influence these effects. Real-world evidence complements clinical trials and informs treatment decisions.

International Journal of Gynecological CancerVol. 36(1)
Heidelberg University (DE), University Hospital Heidelberg (DE), Robert Bosch Hospital (DE), National Center for Tumor Diseases (DE), Baden-Wuerttemberg Cooperative State University (DE)
Openalex Percentile: Top 58%
Ovarian cancer diagnosis and treatment
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