Inhaled nebulised adrenaline delivery in children and adults: A simulation study

The dose delivered using an LMA was approximately four times that of the facemask for infants and young children, and ETT was two times more than LMA. Future research should consider improving the delivery efficiency of nebulised adrenaline via LMA for children of all sizes in appropriate circumstances and investigate improving drug delivery to children via facemask, as well as the safety and efficacy of higher-dosage regimens.

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Publication Details

Journal
Anaesthesia Critical Care & Pain Medicine
Published
2025-11-06
DOI
https://doi.org/10.1016/j.accpm.2025.101667
Primary Topic
Inhalation and Respiratory Drug Delivery
Type
article
Field-Weighted Citation Impact
0.00
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article

Inhaled nebulised adrenaline delivery in children and adults: A simulation study

William Ditcham, Natalie Anderson, Britta Sylvia von Ungern-Sternberg, Barry Clements
Anaesthesia Critical Care & Pain Medicine
Inhalation and Respiratory Drug Delivery
article

Inhaled nebulised adrenaline delivery in children and adults: A simulation study

William Ditcham, Natalie Anderson, Britta Sylvia von Ungern-Sternberg, Barry Clements
article en

Abstract

The dose delivered using an LMA was approximately four times that of the facemask for infants and young children, and ETT was two times more than LMA. Future research should consider improving the delivery efficiency of nebulised adrenaline via LMA for children of all sizes in appropriate circumstances and investigate improving drug delivery to children via facemask, as well as the safety and efficacy of higher-dosage regimens.

Anaesthesia Critical Care & Pain MedicineVol. 45(3)
The Kids Research Institute Australia (AU), The University of Western Australia (AU)
Openalex Percentile: Top 53%
Inhalation and Respiratory Drug Delivery
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