Cancer risks for MSH6 pathogenic variant carriers

These refined, age- and sex-specific risk estimates for MSH6 PV carriers inform tailored surveillance strategies, supporting delayed CRC screening and individualised counselling on risk-reducing surgery for women.

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Publication Details

Journal
European Journal of Cancer
Published
2025-11-06
DOI
https://doi.org/10.1016/j.ejca.2025.116098
Citations
3
Primary Topic
BRCA gene mutations in cancer
Type
article
Field-Weighted Citation Impact
5.45

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article

Cancer risks for MSH6 pathogenic variant carriers

E. Gómez, A. Lam, A. Bakker, Ellis L. Eikenboom et al.
3 citations
European Journal of Cancer
BRCA gene mutations in cancer
5.45
article

Cancer risks for MSH6 pathogenic variant carriers

E. Gómez, A. Lam, A. Bakker, Ellis L. Eikenboom, Floor A.M. Duijkers, Maartje Nielsen, Aung Ko Win, Fonnet E. Bleeker, Sanne W. ten Broeke, Tom G.W. Letteboer, Mark A. Jenkins, Liselotte P. van Hest, Anja Wagner, Mirjam M. de Jong, Christi J. van Asperen, James G. Dowty, Gilles Thomas, Claire C.A. Cornips, Morrison Italia, Fernande C.H.A. Koops
article en
3 citations

Abstract

These refined, age- and sex-specific risk estimates for MSH6 PV carriers inform tailored surveillance strategies, supporting delayed CRC screening and individualised counselling on risk-reducing surgery for women.

European Journal of CancerVol. 231
Leiden University (NL), University Medical Center Groningen (NL), The University of Melbourne (AU), University of Groningen (NL), Leiden University Medical Center (NL), Maastricht University Medical Centre (NL), The Netherlands Cancer Institute (NL), University Medical Center Utrecht (NL), Erasmus MC Cancer Institute (NL), Amsterdam University Medical Centers (NL), Vrije Universiteit Amsterdam (NL), University of Amsterdam (NL)
Vanderbilt University Medical Center, Maag Lever Darm Stichting
Openalex Percentile: Top 4%
BRCA gene mutations in cancer
5.45
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