Central Neurocytoma in the Fourth Ventricle: A Case Report and Review of Cases With This Unusual Presentation Site

Central neurocytoma (CN) is classified as a grade 2 neuronal tumor and is mostly located in the lateral ventricles. In this report, we present the case of a 40-year-old female patient who was admitted due to vertigo and a holocranial headache. Magnetic resonance imaging (MRI) revealed a lesion in the fourth ventricle that appeared heterogeneous and hyperintense. In the T2/fluid attenuated inversion recovery (FLAIR) sequence, numerous cystic areas were observed. Light microscopic examination showed a neoplasm with a neuronal phenotype; areas with neoplastic cells exhibiting a ganglionic appearance were noted, along with immunohistochemical expression of neuronal markers. Currently, the patient is showing clinical improvement.

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Journal
Cureus
Published
2025-11-06
DOI
https://doi.org/10.7759/cureus.96245
Primary Topic
Glioma Diagnosis and Treatment
Type
article
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article

Central Neurocytoma in the Fourth Ventricle: A Case Report and Review of Cases With This Unusual Presentation Site

Erick Gómez‐Apo, Leoncio Tovar-Romero, Aurea Escobar-España, Esli Dimayuga-Velazquez et al.
Cureus
Glioma Diagnosis and Treatment
article

Central Neurocytoma in the Fourth Ventricle: A Case Report and Review of Cases With This Unusual Presentation Site

Erick Gómez‐Apo, Leoncio Tovar-Romero, Aurea Escobar-España, Esli Dimayuga-Velazquez, Wilson Toscano-Rengifo, Luis Adrian Tellez-Manriquez
article en

Abstract

Central neurocytoma (CN) is classified as a grade 2 neuronal tumor and is mostly located in the lateral ventricles. In this report, we present the case of a 40-year-old female patient who was admitted due to vertigo and a holocranial headache. Magnetic resonance imaging (MRI) revealed a lesion in the fourth ventricle that appeared heterogeneous and hyperintense. In the T2/fluid attenuated inversion recovery (FLAIR) sequence, numerous cystic areas were observed. Light microscopic examination showed a neoplasm with a neuronal phenotype; areas with neoplastic cells exhibiting a ganglionic appearance were noted, along with immunohistochemical expression of neuronal markers. Currently, the patient is showing clinical improvement.

CureusVol. 17(11)
Hospital General de México (MX), Hospital de Clínicas (UY), Universidad Nacional Autónoma de México (MX)
Openalex Percentile: Top 54%
Glioma Diagnosis and Treatment
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Central Neurocytoma in the Fourth Ventricle: A Case Report and Review of Cases With This Unusual Presentation Site — Erick Gómez‐Apo, Leoncio Tovar-Romero, et al. · Cureus (2025) | TGRS Research Map | TGRS