Mortality in severe asthma: results from the NORDSTAR cohort
In this nationwide cohort, severe asthma was associated with a significantly higher mortality risk compared to mild-to-moderate asthma. The increased risk was primarily driven by respiratory-related deaths, with OCS use and T2 inflammation as contributing mortality risk factors.
Authors
- Asger Sverrild (ORCID: https://orcid.org/0000-0003-0625-6405)
- Josephine Hjoberg (ORCID: https://orcid.org/0000-0002-7153-1023)
- Anna von Bülow (ORCID: https://orcid.org/0009-0005-3268-785X)
- Olivia Ernstsson (ORCID: https://orcid.org/0000-0002-8920-1372)
- Patrik Sandin (ORCID: https://orcid.org/0000-0002-8730-7392)
- Helena Bäckman (ORCID: https://orcid.org/0000-0002-0553-8067)
- Christer Janson (ORCID: https://orcid.org/0000-0001-5093-6980)
- Jussi Karjalainen (ORCID: https://orcid.org/0000-0001-8747-7087)
- Hannu Kankaanranta (ORCID: https://orcid.org/0000-0001-5258-0906)
- Alan Altraja (ORCID: https://orcid.org/0000-0001-7798-9871)
- Paula Kauppi (ORCID: https://orcid.org/0000-0002-1065-330X)
- Susanne Hansen (ORCID: https://orcid.org/0000-0002-9550-6703)
- Apostolos Bossios (ORCID: https://orcid.org/0000-0002-0494-2690)
- Charlotte Suppli Ulrik (ORCID: https://orcid.org/0000-0001-8689-3695)
- Valentyna Yasinska (ORCID: https://orcid.org/0000-0002-1379-1265)
- Davorka Sekulić
- Kirk Geale (ORCID: https://orcid.org/0000-0001-7241-8471)
- Celeste Porsbjerg (ORCID: https://orcid.org/0000-0003-4825-9436)
- Lauri Lehtimäki (ORCID: https://orcid.org/0000-0003-1586-4998)
- Vibeke Backer (ORCID: https://orcid.org/0000-0002-7806-7219)
- Alexandra Cooper (ORCID: https://orcid.org/0000-0002-6087-7782)
- Bernt Bøgvald Aarli
- Sylvia Packham
Institutions
- Uppsala University (SE)
- University of Copenhagen (DK)
- Karolinska University Hospital (SE)
- University of Helsinki (FI)
- Uppsala University Hospital (SE)
- Tampere University of Applied Sciences (FI)
- Tampere University (FI)
- Seinäjoki University of Applied Sciences (FI)
- Helsinki University Hospital (FI)
- Haukeland University Hospital (NO)
- Frederiksberg Hospital (DK)
- Bispebjerg Hospital (DK)
- Tartu University Hospital (EE)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Karolinska Institutet (SE)
- Sanofi (Netherlands) (NL)
- Tampere University Hospital (FI)
- Tampere University (FI)
- AstraZeneca (Sweden) (SE)
- Quantify Research (Sweden) (SE)
- Metropolitan University (BD)
- GlaxoSmithKline (Sweden) (SE)
- University of Bergen (NO)
- University of Tartu (EE)
- IT University of Copenhagen (DK)
- University of Gothenburg (SE)
- Umeå University (SE)
Publication Details
- Journal
- European Respiratory Journal
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1183/13993003.01289-2025
- Citations
- 2
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.33