Identification of Key Genes Associated with Endoplasmic Reticulum Stress in Calcium Oxalate Kidney Stones

This study identified key genes associated with ERS in CaOx kidney stones through single-cell and transcriptomic analysis. The discovery of these genes provides new insights into the treatment of CaOx kidney stones and offers valuable references for subsequent research. Future research should focus on elucidating the precise roles of these candidate genes in CaOx stone pathogenesis to assess their potential for therapeutic intervention.

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Publication Details

Journal
Genes
Published
2025-11-06
DOI
https://doi.org/10.3390/genes16111338
Primary Topic
Kidney Stones and Urolithiasis Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Identification of Key Genes Associated with Endoplasmic Reticulum Stress in Calcium Oxalate Kidney Stones

Xiaofeng Guan, Zhibo Tan, Wusheng She, Yaoliang Deng et al.
Genes
Kidney Stones and Urolithiasis Treatments
article

Identification of Key Genes Associated with Endoplasmic Reticulum Stress in Calcium Oxalate Kidney Stones

Xiaofeng Guan, Zhibo Tan, Wusheng She, Yaoliang Deng, Biao Wang, Xiang Wang, Zhiwei Tao
article en

Abstract

This study identified key genes associated with ERS in CaOx kidney stones through single-cell and transcriptomic analysis. The discovery of these genes provides new insights into the treatment of CaOx kidney stones and offers valuable references for subsequent research. Future research should focus on elucidating the precise roles of these candidate genes in CaOx stone pathogenesis to assess their potential for therapeutic intervention.

GenesVol. 16(11)
Guangxi Medical University (CN), First Affiliated Hospital of GuangXi Medical University (CN), The Second Nanning People's Hospital (CN)
Openalex Percentile: Top 53%
Kidney Stones and Urolithiasis Treatments
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