The extract of zedoary-turmeric protects rats’ kidneys from damage caused by cisplatin

Cisplatin-induced AKI caused less damage to the kidneys and less production of <i>KIM-1</i>, <i>TNF-</i>α, and <i>Caspase-3</i>, suggesting that a 200 mg/kg combined extract of Zedoary and Turmeric could be used to prevent or lessen kidney damage. These results show that the extract could preserve the kidneys, which could lead to the creation of other treatments for those who are receiving cisplatin.

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Publication Details

Journal
Journal of Advanced Veterinary and Animal Research
Published
2025-01-01
DOI
https://doi.org/10.5455/javar.2025.l950
Primary Topic
Chemotherapy-induced organ toxicity mitigation
Type
article
Field-Weighted Citation Impact
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article

The extract of zedoary-turmeric protects rats’ kidneys from damage caused by cisplatin

Ariyani Noviantari, Sela Septima Mariya, Sukmayati Alegantina, Lisa Andriani Lienggonegoro et al.
Journal of Advanced Veterinary and Animal Research
Chemotherapy-induced organ toxicity mitigation
article

The extract of zedoary-turmeric protects rats’ kidneys from damage caused by cisplatin

Ariyani Noviantari, Sela Septima Mariya, Sukmayati Alegantina, Lisa Andriani Lienggonegoro, Ani Isnawati, Lina Novianti Sutardi, Uly Alfi Nikmah, Ratih Rinendyaputri, Indah Fajarwati, Sunarno Sunarno, Putri Intan, Agus Setiyono, Ekowati Handharyani, Frans Dany
article en

Abstract

Cisplatin-induced AKI caused less damage to the kidneys and less production of <i>KIM-1</i>, <i>TNF-</i>α, and <i>Caspase-3</i>, suggesting that a 200 mg/kg combined extract of Zedoary and Turmeric could be used to prevent or lessen kidney damage. These results show that the extract could preserve the kidneys, which could lead to the creation of other treatments for those who are receiving cisplatin.

Journal of Advanced Veterinary and Animal ResearchVol. 12(3)
IPB University (ID)
Openalex Percentile: Top 54%
Chemotherapy-induced organ toxicity mitigation
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