Molecularly Targeted Cancer Medications and Kidney Health

In this cohort study of patients treated with molecularly targeted anticancer medications associated with an acute rise in sCr, we observed higher incidence and relative rate for kidney dysfunction among treated patients, compared with matched cancer-free patients.

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Publication Details

Journal
JAMA Network Open
Published
2025-11-06
DOI
https://doi.org/10.1001/jamanetworkopen.2025.41221
Citations
2
Primary Topic
Chemotherapy-induced organ toxicity mitigation
Type
article
Field-Weighted Citation Impact
2.94

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article

Molecularly Targeted Cancer Medications and Kidney Health

Jin Long, Ali Raza Khaki, Heather A. Wakelee, Mary Beth Leonard et al.
2 citations
JAMA Network Open
Chemotherapy-induced organ toxicity mitigation
2.94
article

Molecularly Targeted Cancer Medications and Kidney Health

Jin Long, Ali Raza Khaki, Heather A. Wakelee, Mary Beth Leonard, Shuchi Anand, Fauzia Riaz, Susan Ziolkowski, Yutong Zhong, Sunil Reddy, Hannah Morgan‐Cooper
article en
2 citations

Abstract

In this cohort study of patients treated with molecularly targeted anticancer medications associated with an acute rise in sCr, we observed higher incidence and relative rate for kidney dysfunction among treated patients, compared with matched cancer-free patients.

JAMA Network OpenVol. 8(11)
Stanford Health Care (US), Stanford Medicine (US), Stanford University (US)
Bristol-Myers Squibb, Eli Lilly and Company, Pfizer, AstraZeneca, Gilead Sciences, Helsinn, Seagen, National Institutes of Health, Genentech, Chugai Pharmaceutical, National Institute of Diabetes and Digestive and Kidney Diseases, Daiichi Sankyo Europe
Openalex Percentile: Top 8%
Chemotherapy-induced organ toxicity mitigation
2.94
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