Severe acute respiratory distress syndrome in a woman infected with Ascaris lumbricoides

Acute Respiratory Distress Syndrome [ARDS] is a critical condition characterized by severe respiratory failure due to widespread lung inflammation, which can arise from various causes including trauma, infections, and systemic diseases. Among the rare causes is infection with Ascaris lumbricoides, a helminth typically affecting the gastrointestinal tract but capable of causing severe respiratory complications. We present the case of a 41-year-old woman with acute respiratory distress and negative viral and bacterial tests, who was ultimately diagnosed with Ascaris lumbricoides-induced ARDS. Her management included mechanical ventilation, antimicrobial therapy, corticosteroids, and eventually anthelmintic treatment after discovering the parasite. Despite initial deterioration and severe hypoxemia, the patient improved significantly following anthelmintic therapy, allowing extubation on day 8 and ICU discharge on day 12. Helminth-induced ARDS, though rare, should be considered in critically ill patients, especially in endemic regions. Early identification and appropriate therapy can dramatically improve outcomes.

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Publication Details

Journal
˜The œJournal of Critical Care Medicine
Published
2025-10-01
DOI
https://doi.org/10.2478/jccm-2025-0039
Primary Topic
Parasites and Host Interactions
Type
article
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article

Severe acute respiratory distress syndrome in a woman infected with Ascaris lumbricoides

Alexandra Lazăr, Mihai Claudiu Pui
˜The œJournal of Critical Care Medicine
Parasites and Host Interactions
article

Severe acute respiratory distress syndrome in a woman infected with Ascaris lumbricoides

Alexandra Lazăr, Mihai Claudiu Pui
article en

Abstract

Acute Respiratory Distress Syndrome [ARDS] is a critical condition characterized by severe respiratory failure due to widespread lung inflammation, which can arise from various causes including trauma, infections, and systemic diseases. Among the rare causes is infection with Ascaris lumbricoides, a helminth typically affecting the gastrointestinal tract but capable of causing severe respiratory complications. We present the case of a 41-year-old woman with acute respiratory distress and negative viral and bacterial tests, who was ultimately diagnosed with Ascaris lumbricoides-induced ARDS. Her management included mechanical ventilation, antimicrobial therapy, corticosteroids, and eventually anthelmintic treatment after discovering the parasite. Despite initial deterioration and severe hypoxemia, the patient improved significantly following anthelmintic therapy, allowing extubation on day 8 and ICU discharge on day 12. Helminth-induced ARDS, though rare, should be considered in critically ill patients, especially in endemic regions. Early identification and appropriate therapy can dramatically improve outcomes.

˜The œJournal of Critical Care MedicineVol. 11(4)
Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș (RO)
Openalex Percentile: Top 66%
Parasites and Host Interactions
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Severe acute respiratory distress syndrome in a woman infected with Ascaris lumbricoides — Alexandra Lazăr, Mihai Claudiu Pui · ˜The œJournal of Critical Care Medicine (2025) | TGRS Research Map | TGRS