Understanding the complex relationship between amino acid absorption kinetics and postprandial muscle protein synthesis rates in healthy adults and critically ill patients
The enteral provision of free amino acids represents a theoretical, but not practically-relevant, clinical nutrition strategy to mitigate the catabolic response to critical illness. Future studies are warranted to establish targeted protein/amino acid-based interventions to mitigate skeletal muscle atrophy during the metabolic care of critically ill patients.
Authors
- Oliver C. Witard (ORCID: https://orcid.org/0000-0002-5875-8397)
- Konstantinos Prokopidis (ORCID: https://orcid.org/0000-0002-6264-9388)
- Colleen S. Deane (ORCID: https://orcid.org/0000-0002-2281-6479)
Institutions
- University of Liverpool (GB)
- King's College London (GB)
- Southampton General Hospital (GB)
- University Hospital Southampton NHS Foundation Trust (GB)
- NIHR Southampton Biomedical Research Centre (GB)
Publication Details
- Journal
- Current Opinion in Clinical Nutrition & Metabolic Care
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1097/mco.0000000000001181
- Primary Topic
- Clinical Nutrition and Gastroenterology
- Type
- article
- Field-Weighted Citation Impact
- 0.00