Management and Therapeutic Considerations of Hydrogen Peroxide-Induced Necrotizing Gastroenteritis: A Case Report

Necrotizing gastroenteritis is a rare but severe condition characterized by extensive inflammation and mucosal necrosis of the gastrointestinal tract. It is most commonly seen in neonates, infants, and immunocompromised individuals. We present a rare case of a 46-year-old female patient who developed necrotizing gastroenteritis following accidental ingestion of 3% hydrogen peroxide, manifesting as three days of epigastric pain, heartburn, and recurrent emesis. This report details the patient's clinical presentation, diagnostic evaluation, therapeutic strategies, and management course. The case emphasizes the importance of clinical suspicion, timely intervention, and consideration of both surgical and conservative treatment approaches, with particular attention to long-term functional complications and quality of life.

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Publication Details

Journal
Cureus
Published
2025-11-06
DOI
https://doi.org/10.7759/cureus.96224
Primary Topic
Abdominal vascular conditions and treatments
Type
article
Field-Weighted Citation Impact
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article

Management and Therapeutic Considerations of Hydrogen Peroxide-Induced Necrotizing Gastroenteritis: A Case Report

David Hernández González, Frederick M Tiesenga, M Pourmoghadam, Marian Saba et al.
Cureus
Abdominal vascular conditions and treatments
article

Management and Therapeutic Considerations of Hydrogen Peroxide-Induced Necrotizing Gastroenteritis: A Case Report

David Hernández González, Frederick M Tiesenga, M Pourmoghadam, Marian Saba, Olivia Mesdjian, Dolores Ivkovic
article en

Abstract

Necrotizing gastroenteritis is a rare but severe condition characterized by extensive inflammation and mucosal necrosis of the gastrointestinal tract. It is most commonly seen in neonates, infants, and immunocompromised individuals. We present a rare case of a 46-year-old female patient who developed necrotizing gastroenteritis following accidental ingestion of 3% hydrogen peroxide, manifesting as three days of epigastric pain, heartburn, and recurrent emesis. This report details the patient's clinical presentation, diagnostic evaluation, therapeutic strategies, and management course. The case emphasizes the importance of clinical suspicion, timely intervention, and consideration of both surgical and conservative treatment approaches, with particular attention to long-term functional complications and quality of life.

CureusVol. 17(11)
St. George's University (GD), St. George's School (US), West Suburban Medical Center (US)
Openalex Percentile: Top 49%
Abdominal vascular conditions and treatments
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