High-Throughput Tear Proteomics Reveals Multi-Faceted Signatures of Thyroid Eye Disease
Tear proteomics reveals distinct molecular signatures shaped by the combined influences of ophthalmopathy, autoimmunity, and hyperthyroidism throughout the pathogenesis of TED, underscoring the potential of tear proteins as early, noninvasive biomarkers for disease diagnosis.
Authors
- Huifang Zhou (ORCID: https://orcid.org/0000-0002-8636-861X)
- Runchuan Li (ORCID: https://orcid.org/0000-0002-1921-0281)
- Jing Sun (ORCID: https://orcid.org/0000-0001-6284-7862)
- Yining Wei
- Haiyang Zhang (ORCID: https://orcid.org/0000-0002-3511-9955)
- Yang Li (ORCID: https://orcid.org/0000-0001-9055-2332)
- Yi Pan (ORCID: https://orcid.org/0000-0002-2766-3096)
Institutions
- Shanghai Ninth People's Hospital (CN)
- Jiangsu Province Hospital (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1167/iovs.66.14.11
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Westlake University
- National Natural Science Foundation of China
- Science and Technology Commission of Shanghai Municipality
- Shanghai Jiao Tong University