Unraveling the genetic landscape of ALS in Greece: identification of known and novel causative variants in a 353-patient cohort
Our results reveal the distinct genetic profile of Greek ALS patients. These findings will have an impact on genetic counseling, the design of diagnostic gene panels for the Greek population and on genotype-specific therapeutic interventions. Understanding the genetic causes of ALS in different populations is becoming increasingly important, especially with the advent of personalized medicine.
Authors
- Eleftheria Koropouli (ORCID: https://orcid.org/0000-0001-8537-4471)
- Georgia Karadima (ORCID: https://orcid.org/0000-0001-7003-5717)
- Ioanna Spyropoulou (ORCID: https://orcid.org/0000-0001-7801-3395)
- Maria Petraki (ORCID: https://orcid.org/0000-0002-4855-3718)
- Zoi Kontogeorgiou (ORCID: https://orcid.org/0000-0002-9796-8178)
- Chrysoula Koniari
- Ariadne Daponte (ORCID: https://orcid.org/0000-0002-6292-858X)
- Dimitrios Miltiadis Vrachnos
- Μάριος Πάνας
- E. Kapaki (ORCID: https://orcid.org/0000-0003-0570-0324)
- Stavroula Aristeidou
- Georgios Koutsis (ORCID: https://orcid.org/0000-0002-8980-8377)
- Leonidas Stefanis
- Periklis Makrythanasis
- Chrisoula Kartanou
- Theodoros Loupis
- Michail Rentzos
- Nikolaos Ragazos
Institutions
- University of Geneva (CH)
- National and Kapodistrian University of Athens (GR)
- Academy of Athens (GR)
- Biomedical Research Foundation of the Academy of Athens (GR)
- Eginition Hospital (GR)
Publication Details
- Journal
- Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1080/21678421.2025.2582828
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00