Clinical application of metagenomic next-generation sequencing in the diagnosis of severe pneumonia pathogens
Compared with CMT methods, mNGS has significant advantages in pathogen detection for severe pneumonia. Owing to its broad detection range and high sensitivity, mNGS serves as a valuable complementary approach to traditional culture-based methods.
Authors
- Quan Ke Thai (ORCID: https://orcid.org/0000-0002-2264-2579)
- Handong Zou (ORCID: https://orcid.org/0000-0002-0709-0788)
- Wei Wu (ORCID: https://orcid.org/0000-0002-1092-603X)
- Caitao Dong (ORCID: https://orcid.org/0000-0003-0003-9135)
- Jingdi Chen (ORCID: https://orcid.org/0000-0001-7440-4743)
- Hang Gao (ORCID: https://orcid.org/0000-0001-7244-3263)
- Jing Yang (ORCID: https://orcid.org/0000-0002-3833-9996)
- Mengmeng Guo (ORCID: https://orcid.org/0000-0002-7606-4954)
- Raojuan Huang
- Ying Zhang (ORCID: https://orcid.org/0000-0001-5476-1524)
Institutions
- Wuhan University (CN)
- Renmin Hospital of Wuhan University (CN)
- Wuhan General Hospital of Guangzhou (CN)
- Jingning County People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-11-06
- DOI
- https://doi.org/10.3389/fcimb.2025.1661213
- Primary Topic
- Bacterial Identification and Susceptibility Testing
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hubei Province
- Wuhan University