Asymmetric dimethylarginine mediates oxidative stress and atrial remodeling in HL-1 cells
ADMA may induce TGF-β1 expression by enhancing NOX-ROS levels, leading to myocardial oxidative damage and atrial remodeling, which provides new insights into AF pathophysiology.
Authors
- Wei Xia (ORCID: https://orcid.org/0000-0001-6480-3265)
- Ming Zhang (ORCID: https://orcid.org/0000-0002-6027-4594)
- Chengyun Yu
Institutions
- Qingdao University (CN)
- Weifang Medical University (CN)
- Shanghai Jiao Tong University (CN)
- Qingdao Municipal Hospital (CN)
- Songjiang District Central Hospital (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-11-04
- DOI
- https://doi.org/10.3389/fmed.2025.1696845
- Primary Topic
- Nitric Oxide and Endothelin Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00