Safety profile of Japanese encephalitis vaccines: a comprehensive analysis of vaccine adverse event reports from 1993 to 2025

This study revealed the reporting patterns of JEV vaccine adverse events in the VAERS database, indicating that a considerable proportion of reports were serious events, and allergic reactions such as pruritus, rash, and urticaria were prominent. The observed overlap between spontaneous reporting and online search trends suggests public awareness and information dissemination influence reporting patterns. These findings underscore the need for continued JEV safety surveillance and further investigation.