Evolution of the Indications and Outcomes of Total Pancreatectomy
The use of TP has dramatically increased in recent years, primarily for adenocarcinoma alongside increased use of neoadjuvant therapy and ever-expanding criteria for anatomic resectability. Operative complexity has significantly increased with resultant increased perioperative morbidity. TP remains a higher-risk procedure, specifically with en bloc vascular resections, emphasizing the importance of appropriate patient selection, preoperative patient education, and thoughtful postoperative and long-term management.
Authors
- Patrick P. Starlinger (ORCID: https://orcid.org/0000-0002-4666-5337)
- Mark Joseph Truty (ORCID: https://orcid.org/0000-0003-3776-527X)
- Cornelius A. Thiels (ORCID: https://orcid.org/0000-0003-3654-8601)
- Hallbera Gudmundsdottir (ORCID: https://orcid.org/0000-0002-1297-2769)
- Rory L. Smoot (ORCID: https://orcid.org/0000-0001-8543-661X)
- Susanne G Warner
- Stella K Adjei Antwi
- Michael L. Kendrick (ORCID: https://orcid.org/0009-0005-7960-3254)
Institutions
- Thiel College (US)
- Mayo Clinic in Arizona (US)
Publication Details
- Journal
- Journal of the American College of Surgeons
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1097/xcs.0000000000001642
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00