Visible-light-induced regioselective amidoperoxidation of alkenes
A novel metal-free, photoinduced three-component amidoperoxidation of alkenes, oxime ester, and <i>tert</i>-butyl hydroperoxide (TBHP) has been realized. This protocol achieves concurrent C-O (peroxy) and C-N bond formation at room temperature under visible-light irradiation, with distinguished chemo- and regioselectivity. This method delivers β-peroxy amides directly in moderate to excellent yields with a broad substrate scope.
Authors
- Zhuang‐Ping Zhan (ORCID: https://orcid.org/0000-0002-6310-8663)
- Jie Lü (ORCID: https://orcid.org/0000-0003-0690-4732)
- Cai Gao
- Zhenqiang Zhang (ORCID: https://orcid.org/0009-0004-9314-5029)
- Z. Zhao (ORCID: https://orcid.org/0009-0005-3492-9007)
Institutions
- Xiamen University (CN)
- Kunming Institute of Precious Metals (CN)
Publication Details
- Journal
- Organic & Biomolecular Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5ob01561h
- Citations
- 1
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.94