[(Ph <sub>3</sub> P)Ag(OCF <sub>2</sub> CF <sub>2</sub> SO <sub>2</sub> F)] <sub>2</sub> : A Thermally Stable Reagent for Fluorosulfonyl Tetrafluoroethoxylation
A thermally stable, light-insensitive crystalline fluorosulfonyl tetrafluoroethoxylating reagent, [(Ph<sub>3</sub>P)Ag(OCF<sub>2</sub>CF<sub>2</sub>SO<sub>2</sub>F)]<sub>2</sub> (<b>1</b>), was developed. The reagent demonstrates high nucleophilicity toward diverse electrophiles, including benzyl bromides/chlorides, alkyl bromides, triflates, and secondary alkyl nosylates. The incorporated sulfonyl fluoride moiety demonstrates remarkable versatility, undergoing facile conversion to both sulfonates and sulfones through reactions with various nucleophiles. Furthermore, we have successfully applied this chemistry to prepare a series of photoacid generators with potential applications in photolithography technology.
Authors
- Shunli Chen (ORCID: https://orcid.org/0000-0002-1345-8307)
- Qilong Shen (ORCID: https://orcid.org/0000-0001-5622-153X)
- Long Lü
Institutions
- Shanghai Institute of Organic Chemistry (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1021/acs.joc.5c01771
- Primary Topic
- Fluorine in Organic Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00